Diabetes Research Review

Read the latest edition of Australian Diabetes Research Review Diabetes_Research_Review_Issue_113

This edition features:

–  Dual SGLT-1/2 inhibition with sotagliflozin in T1DM
–  Adding semaglutide vs. sitagliptin in T2DM uncontrolled with metformin/sulfonylurea
–  Long-term weight loss with metformin or lifestyle intervention
–  Dapagliflozin ±saxagliptin in T2DM and CKD
–  Data-driven subgroups versus clinical feature models for T2DM progression/response
–  Suspend-before-low insulin pump technology in hypoglycaemia-prone T1DM
–  Primary care-led weight-management intervention for T2DM
–  Semaglutide added to SGLT-2 inhibitor in T2DM
–  Structured SMBG ±TeleCare support in non-insulin treated T2DM
–  Physical exercise and intermittently viewed CGM performance in T1DM

Definitioner

Insulin pump

An insulin pump is a small, battery-powered device that mechanically pumps measured amounts of insulin through an infusion set into the body. THE PUMP IS NOT AUTOMATIC. You program and control it, and you must perform four to six blood glucose tests daily to ensure delivery of appropriate amounts of insulin by the pump.

Insulin

A hormone produced by the beta cells in the pancreas. Insulin is needed by the body to regulate the production and use of glucose.

Hypoglycaemia

Also known as low blood sugar. It occurs when blood glucose levels drop to below 4 mmol/l. This can happen if a person with diabetes has taken too much insulin or has exercised more than usual. Symptoms of hypoglycaemia include dizziness, shakiness, rapid heartbeat, sudden hunger, cold or clammy skin, fuzzy vision, confusion, mood changes, and tingling or numbness in the hands, arms, tongue, or lips. Hypoglycaemia can occur even while using an insulin pump and, if left untreated, can lead to unconsciousness and diabetic coma. Pre-Diabetes – blood glucose (sugar) levels higher than normal but not high enough to be called diabetes. People with pre-diabetes may or may not develop diabetes. Other names for pre-diabetes are impaired glucose tolerance, impaired fasting glucose, borderline, subclinical, chemical, or latent diabetes.

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