Diabetes-specific nutritional supplements increase glp-1, while providing complete and balanced nutrition*1
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The Australian Diabetes Society Type 2 Diabetes (T2D) Glycaemic Management Algorithm suggests lifestyle intervention (diet and exercise) as the first step of managing blood glucose levels in T2D, as well as throughout the treatment strategy, using anti-hyperglycaemic medications.2
Benefits of diabetes-specific nutritional supplements
There is emerging and significant evidence that diabetes-specific nutritional supplements (DSNS) can help to significantly improve blood glucose levels in people with diabetes. A recent meta-analysis showed that in people with type 1 or type 2 diabetes, DSNS were associated with reduced:3
- HbA1c
- post-prandial glucose levels
- incremental glucose response
- mean blood glucose
- glucose variability
- mean administered insulin dose.
Further studies have shown that DSNS are associated with increased glucagon-like peptide 1 (GLP-1) and improvements in glycaemic management.1,4,5
A network meta-analysis of randomised controlled trials comparing the effects of anti-hyperglycaemic medications on muscle mass in people with T2D revealed that 40% of the weight lost through GLP-1 medications (Semaglutide) is fat free mass including skeletal muscle.6
A nutritionally complete and balanced DSNS may be considered to be used in conjunction with GLP-1 medications to help provide high quality protein and vitamins and minerals important for muscle health.7
DSNS make a good breakfast replacement
In a randomised controlled study, newly diagnosed drug naïve people with T2D were treated with either lifestyle intervention (nutritional education and exercise) or lifestyle intervention plus a DSNS for 4 weeks and glycaemic outcomes were assessed using continuous glucose monitoring.8 Both groups showed improvements in:
- body weight
- insulin sensitivity
- fasting plasma glucose
- 2-hour postprandial glucose.
Strikingly, replacing breakfast with a DSNS resulted in a greater improvement in time-in-range and systolic blood pressure. The improvement in time-in-range was 13.8% in the lifestyle plus DSNS group compared with 7.3% in the lifestyle only group.8
Recommend DSNS to reduce the complexities of T2D management
The high protein, fibre and slow-release carbohydrate blend of DSNS, along with their ease of use, is ideal for people with T2D that have many decisions to make in managing their diabetes.
Consuming Glucerna® for breakfast** has been clinically shown to help:
- Reduce blood glucose levels by 38% from day 1*¹
- Increase GLP-1 secretion by 280% from day 1*¹
- Keep blood glucose levels within target range up to 90% of the time within 4 weeks^8
Choose the diabetes-specific nutritional supplement that has been clinically proven with over 30 years of scientific evidence.9
GLUCERNA® IS AVAILABLE IN PHARMACIES. FOR MORE INFORMATION VISIT GLUCERNA.COM.AU
Food for Special Medical Purposes. Use under medical supervision.
DSNS: diabetes-specific nutritional supplements. GLP-1: glucagon-like peptide 1. NHMRC: National Health and Medical Research Council. T2D: type 2 diabetes.
*A randomised controlled trial comparing Glucerna to an oatmeal breakfast in type 2 diabetes patients (n=32) found 280% higher postprandial GLP-1 secretion and 38% lower postprandial blood glucose levels with Glucerna compared to oatmeal (based on individual percent changes).
**When Glucerna is used as part of a diabetes management plan including a healthy diet and exercise.
^When taken as a breakfast replacement as part of a diabetes management plan, people with diabetes consuming Glucerna kept blood glucose within the target glucose range of 3.9 – 10.0mmol/L for an average of 89.5% of the time. The study utlilised a previous Glucerna formulation.
References:
1. Devitt A, et al. J Diabetes Res Clin Metab. 2012;1(1):20.
2. Australian Diabetes Society. Australian Blood Glucose Treatment Algorithm for Type 2 Diabetes. Available at: https://treatment.diabetessociety.com.au/plan/
3. Sanz-París A, et al. Clin Nutr. 2020;39(11):3273–3282.
4. Mottalib A, et al. Nutrients. 2016;8(7):443.
5. Angarita Dávila L, et al. Nutrients. 019;11(7):1477.
6. Ida S, et al. Curr Diabetes Rev. 2021;17(3):293–303.
7. Argiles J, et al. J American Medical Directors Assoc. 2016;17(9):789-796.
8. Peng, J., et al. Br J Nutr 2019: 121(5):560-566.
9. National Library of Medicine, PubMed. Available at: https://pubmed.ncbi.nlm.nih.gov/?term=Glucerna&filter=pubt.clinicaltrial&filter=pubt.randomizedcontrolledtrial&filter=pubt.systematicreview (accessed May 2024)
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Customer Service 1800 225 311. www.abbottnutrition.com.au. ANZ.2024.49043.GLU.1. June 2024.